Iram Murtaza

Professor and Chairperson
Department of Biochemistry, Quaid-i-Azam University Islamabad

Pakistan

This profile has been endorsed by The Pakistan Academy of Sciences

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  • Mentoring
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Expertise

Biography

To explore the modulation of Cellular signaling responses for the potential highly specific diagnostics and therapeutics provisions.

 

Featured

Award

2010

International Young Scientist Award (Chinese Academy of Sciences)

Academic paper

2008

Down-regulation of Catalase and Oxidative Modification of Protein Kinase CK2 Lead to the Failure of Apoptosis Repressor with Caspase Recruitment Domain to Inhibit Cardiomyocyte Hypertrophy
Academic paper

2009

miR-23a functions downstream of NFATc3 to regulate cardiac hypertrophy
Academic paper

2013

Therapeutic potential of tumour necrosis factor-alpha antagonists in patients with chronic heart failure
Academic paper

2013

miR-761 regulates the mitochondrial network by targeting mitochondrial fission factor
Academic paper

2014

Cardiac hypertrophy is negatively regulated by miR-541
Academic paper

2017

Interplay of mitochondria apoptosis regulatory factors and microRNAs in valvular heart disease
Academic paper

2019

Interplay of N acetyl cysteine and melatonin in regulating oxidative stress-induced cardiac hypertrophic factors and microRNAs
Book

2020

An Overview of Non-coding RNAs and Cardiovascular System
Book

2020

Prospective Advances in Non-coding RNAs Investigation
Academic paper

2020

Pistacia integerrima alleviated Bisphenol A induced toxicity through Ubc13/p53 signalling
Academic paper

2020

Melatonin Act as an Antidepressant via Attenuation of Neuroinflammation by Targeting Sirt1/Nrf2/HO-1 Signaling
Academic paper

2020

Melatonin prevents neuroinflammation and relieves depression by attenuating autophagy impairment through FOXO3a regulation
Academic paper

2020

Engineering electroactive and biocompatible tetra (aniline)-based terpolymers with tunable intrinsic antioxidant properties in vivo
Grant

2011

TWAS –COMSTECH research grant. Therapeutic interventional study for lethal pathological disorders by employing ROS regulating endogenous factors.

Grant

2011

TWAS –COMSTECH research grant. Therapeutic interventional study for lethal pathological disorders by employing ROS regulating endogenous factors.

Grant

2011

TWAS –COMSTECH research grant. Therapeutic interventional study for lethal pathological disorders by employing ROS regulating endogenous factors.

Grant

2009

Novel therapeutic intervention for inhibiting cardiac hypertrophy by elucidating molecular signaling mechanism of specific transcription factors

Grant

2018

Regulation of mitochondrial functioning to inhibit cardiomyocytes hypertrophy leading to heart failure.

Grant

2019

Development of Cardiac Specific Neurohormonal Based Diagnostic Marker for Cardiac Failure Detection at early stage

Grant

2020

PSF Consortium Project on Cardiovascular Molecular Diagnostics

Academic paper

2021

Melatonin abated Bisphenol A–induced neurotoxicity via p53/PUMA/Drp-1 signaling.